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Mesenchymal Stem Cell Therapy Found Compatible to COVID-19 Treatment

MSC Treatment for COVID-19
COVID-19 have conquered whole world . The infected  cases are increasing day by day  and struggles are progressing hardly in  beating this deadly virus. Severel clinical trials have set to find an ultimate solution to end up this virus. The article, published in the scientific journal Aging and Disease (2020) states that mesenchymal stem cells are a safe and effective approach to COVID-19 treatment and now there are official data on the recovery of at least 7 patients with COVID-19 courtesy of mesenchymal stem cell treatment. All patients had fever,suffocation due to shortness of breath , decreased oxygen saturation, pneumonia.

Stem cells are special human cells that are able to develop into many different cell types ranging from muscle cells to brain cells. Adult stem cells can be isolated from the body depending on tisue. One can take from donor's bone marrow , from a live person's blood and even from the blood of umbilical cord when a baby is born. Researchers sayt hat stem cell based therapies can be used to serious illness treatment.

Mesenchymal Stem Cells (MSCs) are traditionally found in bone marrow but it can also isolate from cord blood , peripheral blood, fallopian tube, and fetal liver and lung. Mesenchymal stem cells are a powerful immunomodulatory and anti-inflammatory agent, they normalize the function of the immune system, altered by COVID-19.

The upper respiratory infection by COVID-19 following the suffocation leading most people to death.  The virus causes a cytokine storm in the body, that is, virus-activated immune cells secrete an excess of cellular hormones (cytokines) that have damaging effects on their own tissues, promote swelling, fibrosis (growth of connective tissue) and functional insufficiency.

After the intravenous transplantation of MSCs what happening is that, significant population of cells accumulates in the lung, which they alongside immunomodulatory effect could protect alveolar epithelial cells, reclaim the pulmonary microenvironment, prevent pulmonary fibrosis, and reduce the level of C-reactive protein, which is a major marker of inflammation.Reduce the level of such a powerful pro-inflammatory protein as TNF-a.Increase the level of anti-inflammatory protein IL-10 and finally cure the lung dysfunction.

So let's hope a mass recovery from the deadly virus COVID-19.

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